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SEROMYCIN (CYCLOSERINE): ADVERSE REACTIONS / SIDE EFFECTS

Most adverse reactions occurring during therapy with Cycloserine (Seromycin) involve the nervous system or are manifestations of drug hypersensitivity. The following side effects have been observed in patients receiving Seromycin:

Nervous system symptoms (which appear to be related to higher dosages of the drug, i.e., more than 500 mg daily): drowsiness and somnolence, convulsions, headache, dysarthria, tremor, vertigo, confusion and disorientation with loss of memory, psychoses, possibly with suicidal tendencies, hyperirritability, character changes, aggression, hyperreflexia, paresis, paresthesia, major and minor (localized) clonic seizures, coma.

Cardiovascular: sudden development of congestive heart failure in patients receiving 1 to 1.5 g of Seromycin daily has been reported.

Allergy (apparently not related to dosage): skin rash

Miscellaneous: elevated serum transaminase, especially in patients with preexisting liver disease



Seromycin (Cycloserine) related pharmaceutical drugs and medications

Trade name of the drug Pharmaceutical forms and doses Companies
Intrapen - Ampicillin Anhydrous
  • Capsules; Oral; Ampicillin Anhydrous 500 mg
  • Suspension; Oral; Ampicillin Anhydrous 250 mg / 5 ml
  • Intra Laboratorios
  • Hydrazid - Isoniazid
  • Tablets; Oral; Isoniazid 50 mg
  • Otsuka Pharmaceutical


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